Ischemic stroke and peripheral arterial thromboembolism in a patient with Crohn's disease: a case presentation

Tobias Freilinger; Eva Riedel; Markus Holtmannspötter; Martin Dichgans; Nils Peters

doi:10.1016/j.jns.2007.08.035

Ischemic stroke and peripheral arterial thromboembolism in a patient with Crohn's disease: a case presentation

J Neurol Sci. 2008 Mar 15;266(1-2):177-9. doi: 10.1016/j.jns.2007.08.035. Epub 2007 Sep 27.

Authors

Tobias Freilinger¹, Eva Riedel, Markus Holtmannspötter, Martin Dichgans, Nils Peters

Affiliation

¹ Department of Neurology, Klinikum Grosshadern, Ludwig-Maximilians-University, Marchioninistr. 15, 81377 Munich, Germany. [email protected]

PMID: 17904158
DOI: 10.1016/j.jns.2007.08.035

Abstract

Both ischemic stroke and peripheral arterial thromboembolism have been described as extraintestinal complications of inflammatory bowel disease. Here, we present the first case with direct cooccurrence of ischemic stroke and peripheral thromboembolism in a 39-year-old patient with Crohn's disease. A pathophysiological model explaining this cooccurrence as well as the significance of prothrombotic risk factors ("hypercoaguable state") in the setting of inflammatory bowel disease and stroke are discussed.

Publication types

Case Reports

MeSH terms

Anticoagulants / therapeutic use
Aspirin / therapeutic use
Blood Cell Count
Blood Coagulation / physiology
Bone Marrow / pathology
Brain Ischemia / complications*
Crohn Disease / blood
Crohn Disease / complications*
Electrocardiography
Electrocardiography, Ambulatory
Heparin / therapeutic use
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Platelet Aggregation Inhibitors / therapeutic use
Posterior Cerebral Artery / pathology
Risk
Stroke / complications*
Stroke / etiology
Thromboembolism / blood
Thromboembolism / complications*
Thromboembolism / diagnostic imaging
Tomography, X-Ray Computed
Ultrasonography, Doppler, Duplex

Substances

Anticoagulants
Platelet Aggregation Inhibitors
Heparin
Aspirin