"PIKing" the winner for phosphatidylinositol 3-kinase inhibitors in ErbB2-positive breast cancer: let's not "PTENed" it's easy!

Clin Cancer Res. 2007 Oct 1;13(19):5661-2. doi: 10.1158/1078-0432.CCR-07-1698.
No abstract available

Publication types

  • Editorial
  • Comment

MeSH terms

  • Animals
  • Breast Neoplasms / enzymology*
  • Breast Neoplasms / metabolism
  • Enzyme Inhibitors / pharmacology*
  • Gene Expression Regulation, Neoplastic*
  • Humans
  • Models, Biological
  • Mutation
  • PTEN Phosphohydrolase / genetics
  • Phosphatidylinositol 3-Kinases / metabolism*
  • Receptor, ErbB-2 / biosynthesis*
  • Signal Transduction

Substances

  • Enzyme Inhibitors
  • Phosphatidylinositol 3-Kinases
  • Receptor, ErbB-2
  • PTEN Phosphohydrolase
  • PTEN protein, human