Stable analogues of aminoacyl-tRNA for inhibition of an essential step of bacterial cell-wall synthesis

J Am Chem Soc. 2007 Oct 24;129(42):12642-3. doi: 10.1021/ja0749946. Epub 2007 Oct 2.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteria / metabolism*
  • Cell Wall / metabolism*
  • Enzymes / chemistry
  • Inhibitory Concentration 50
  • Models, Biological
  • Models, Chemical
  • Organophosphorus Compounds / chemistry
  • Peptidoglycan / chemistry*
  • Phosphorylation
  • RNA, Transfer, Amino Acyl / chemistry*
  • Staphylococcus aureus / metabolism
  • Streptococcus pneumoniae / metabolism

Substances

  • Enzymes
  • Organophosphorus Compounds
  • Peptidoglycan
  • RNA, Transfer, Amino Acyl
  • phosphoramidite