Finding disease candidate genes by liquid association

Genome Biol. 2007;8(10):R205. doi: 10.1186/gb-2007-8-10-r205.

Abstract

A novel approach to finding candidate genes by using gene expression data through liquid association is developed and used to identify multiple sclerosis susceptibility candidate genes.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Computational Biology / methods*
  • Excitatory Amino Acid Transporter 1 / metabolism
  • Finland
  • Gene Expression*
  • Genetic Predisposition to Disease / genetics*
  • Genetic Testing / methods*
  • Genomics / methods*
  • Genotype
  • Humans
  • Multiple Sclerosis / genetics
  • Protein Kinase C-alpha / metabolism

Substances

  • Excitatory Amino Acid Transporter 1
  • SLC1A3 protein, human
  • PRKCA protein, human
  • Protein Kinase C-alpha