Abstract
Tamoxifen has been in the center of management of hormone-sensitive breast cancer. Furthermore, it represents the best example of chemo-prevention: It reduces the incidence of invasive breast cancer. However, it has some side effects, several of them are severe. Oncologists, hematologists, internal medicine specialists and gynecologists must know this agent in detail. Authors report a very rare side effect, thrombocytopenia, and discuss it briefly.
MeSH terms
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Antineoplastic Agents, Hormonal / adverse effects*
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Antineoplastic Agents, Hormonal / therapeutic use
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Bone Marrow / pathology
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Breast Neoplasms / diagnosis
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Breast Neoplasms / drug therapy*
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Breast Neoplasms / surgery
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Carcinoma, Ductal / diagnosis
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Carcinoma, Ductal / drug therapy*
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Carcinoma, Ductal / surgery
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Female
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Humans
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Middle Aged
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Tamoxifen / adverse effects*
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Tamoxifen / therapeutic use
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Thrombocytopenia / chemically induced*
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Thrombocytopenia / diagnosis*
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Withholding Treatment
Substances
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Antineoplastic Agents, Hormonal
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Tamoxifen