Video capsule endoscopy (VCE) is a major advance in visualization of the small intestine and has been widely used for small intestinal involvement. We have developed a new capsule endoscope in collaboration with Olympus Medical Systems. Its features are, upgrade resolution, depth of the field, and brightness of the image, by improving the optical system, contained with the new function to adjust the level of lighting automatically coordinate with the brightness around, and original handy displayed real-time viewer. VCE is a new device which contributes to the diagnosis of nonsteroidal anti-inflammatory drug (NSAID) induced enteropathy, however, attention should be paid to retention of the capsule due to the stenosis of diaphragm induced by NSAID.