Isolation and characterization of a novel helicobacter species, "Helicobacter macacae," from rhesus monkeys with and without chronic idiopathic colitis

J Clin Microbiol. 2007 Dec;45(12):4061-3. doi: 10.1128/JCM.01100-07. Epub 2007 Oct 10.

Abstract

Chronic idiopathic colitis is a common clinical entity in young captive rhesus monkeys. Eight isolates, cultured from five monkeys in colony 1 with endemic diarrhea and three from colony 2 without diarrhea, were grown under microaerobic conditions on selective agar and were classified by full 16S rRNA sequence, biochemical, and phenotypic analysis as a novel helicobacter, "Helicobacter macacae" (proposed name). All eight strains of H. macacae had 99.5% identical 16S rRNA sequences.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Animals
  • Bacterial Typing Techniques
  • Colitis / epidemiology
  • Colitis / microbiology
  • Colitis / veterinary*
  • DNA, Bacterial / chemistry
  • DNA, Bacterial / genetics
  • DNA, Ribosomal / chemistry
  • DNA, Ribosomal / genetics
  • Diarrhea / epidemiology
  • Diarrhea / microbiology
  • Endemic Diseases
  • Genes, rRNA
  • Helicobacter / classification*
  • Helicobacter / genetics
  • Helicobacter / isolation & purification*
  • Helicobacter / physiology
  • Macaca mulatta / microbiology*
  • Molecular Sequence Data
  • Phylogeny
  • RNA, Bacterial / genetics
  • RNA, Ribosomal, 16S / genetics
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid

Substances

  • DNA, Bacterial
  • DNA, Ribosomal
  • RNA, Bacterial
  • RNA, Ribosomal, 16S

Associated data

  • GENBANK/AF333338