Abstract
Synthetic studies of annonaceous acetogenins starting from (-)-muricatacin (1a) or (+)-muricatacin are described, involving (-)-muricatacin (1a), mono-THF acetogenin, solamin (2), reticulatacin (3), (15R, 16R, 19S, 20S)-cis-solamin (4a) and (15S, 16S, 19R, 20R)-cis-solamin (4b), non-adjacent bis-THF acetogenin, 4-deoxygigantecin (5), and epoxide-bearing acetogenin, (15S, 16R, 19S, 20R)-diepomuricanin (6a).
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Acetogenins / chemical synthesis*
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Acetogenins / chemistry
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Antineoplastic Agents, Phytogenic / chemical synthesis*
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Antineoplastic Agents, Phytogenic / chemistry
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Benzethonium / chemical synthesis*
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Benzethonium / chemistry
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Furans / chemistry*
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Molecular Structure
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Stereoisomerism
Substances
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Acetogenins
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Antineoplastic Agents, Phytogenic
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Furans
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muricatacin
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Benzethonium