Pulmonary Kaposi sarcoma in six children

Pediatr Radiol. 2007 Dec;37(12):1224-9. doi: 10.1007/s00247-007-0632-9. Epub 2007 Oct 17.

Abstract

Background: Pulmonary involvement in Kaposi sarcoma is rare in children and can be difficult to distinguish from other pathology.

Objective: To describe the radiological findings in paediatric pulmonary Kaposi sarcoma.

Materials and methods: Sequential chest radiographs of six children and CT scans of four of these children were evaluated retrospectively. Their ages ranged from 18 months to 10 years; four were male and two were female. All six children were HIV-positive. The observers were two radiologists.

Results: Chest radiographs revealed air-space (100%) and reticular (83%) opacification in the mid- and lower lung zones; pleural effusions were present in 83% of the children. All the children showed progressive air-space opacification on follow-up radiography. CT demonstrated bilateral air-space opacification in a perihilar distribution in all the children; reticular opacification was seen in 75%. All the children had mediastinal and axillary lymphadenopathy; 75% had bilateral hilar lymphadenopathy.

Conclusion: In both adults and children, chest radiography demonstrates perihilar and lower zone involvement. Pleural effusions are more common on radiographs in children. Air-space disease and lymphadenopathy are much more common on CT in children than adults.

MeSH terms

  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Lung Neoplasms / diagnostic imaging*
  • Male
  • Radiography, Thoracic
  • Sarcoma, Kaposi / diagnostic imaging*
  • Tomography, X-Ray Computed