The aim of this study is to discuss the occurrence mechanism of the brain injury analytically and experimentally. In this paper, first, an experimental system to do an impact experiment was presented. The pressure changes inside a brain agar phantom were measured. Second, a three-dimensional FEM model of the impact experiment was constructed. From the results of the fundamental analysis, the transmitted pressure inside the brain agar phantom could be presented. The comparison of the computer simulation and experimental results showed that the negative pressure values, same as the positive pressure occurred in the coup side region of the agar, also appeared in the contrecoup side region of the agar.