Treatment options for the management of acute leukaemia relapsing following an allogeneic transplant

B E Shaw; N H Russell

doi:10.1038/sj.bmt.1705888

Treatment options for the management of acute leukaemia relapsing following an allogeneic transplant

Bone Marrow Transplant. 2008 Mar;41(5):495-503. doi: 10.1038/sj.bmt.1705888. Epub 2007 Oct 22.

Authors

B E Shaw¹, N H Russell

Affiliation

¹ Section of Haemato-Oncology, Royal Marsden Hospital, Surrey, UK. [email protected]

PMID: 17952130
DOI: 10.1038/sj.bmt.1705888

Abstract

The management of acute leukaemia which relapses following an allogeneic stem cell transplant remains a major challenge. In this review we summarize the outcomes of the currently available treatment modalities and discuss emerging novel approaches.

Publication types

Review

MeSH terms

Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Immunotherapy, Adoptive
Leukemia, Myeloid, Acute / therapy*
Neoplasm, Residual
Precursor Cell Lymphoblastic Leukemia-Lymphoma / therapy*
Protein Kinase Inhibitors / therapeutic use
Recurrence
Transplantation, Homologous

Substances

Protein Kinase Inhibitors