Hepatitis B virus and hepatitis C virus in pregnant Sudanese women

Virol J. 2007 Oct 24:4:104. doi: 10.1186/1743-422X-4-104.

Abstract

Background: The epidemiology of viral hepatitis during pregnancy is essential for health planners and programme managers. While much data exist concerning viral hepatitis during pregnancy in many African countries, no proper published data are available in Sudan.

Aim: The study aimed to investigate the sero-prevalence and the possible risk factors for hepatitis B virus (HBV) and hepatitis C virus (HCV) among antenatal care attendants in central Sudan.

Methods: During 3 months from March-June 2006, sera were collected from pregnant women at Umdurman Maternity Hospital in Sudan, and they were tested for markers of hepatitis B virus (HBVsAg) and HCV.

Results: HBVsAg was detected in 41 (5.6%) out 728 women, Anti-HCV was detected in 3 (0.6%) out of 423 women, all of them were not aware of their condition. Age, parity, gestational age, residence, history of blood transfusion, dental manipulations, tattooing and circumcision did not contribute significantly to increased HBVsAg sero-positivity.

Conclusion: Thus 5.6% of pregnant women were positive for HBVsAg irrespective of their age, parity and socio-demographic characteristics. There was low prevalence of Anti-HCV.

MeSH terms

  • Adult
  • Cross-Sectional Studies
  • Female
  • Hepacivirus / isolation & purification*
  • Hepatitis B / epidemiology*
  • Hepatitis B / virology
  • Hepatitis B Surface Antigens / blood
  • Hepatitis B virus / isolation & purification*
  • Hepatitis C / epidemiology*
  • Hepatitis C / virology
  • Hepatitis C Antibodies / blood
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / epidemiology*
  • Pregnancy Complications, Infectious / virology*
  • Risk Factors
  • Sudan / epidemiology

Substances

  • Hepatitis B Surface Antigens
  • Hepatitis C Antibodies