Late coronary stent thrombosis complicating urologic surgery

Eur Urol. 2008 Jul;54(1):221-5; quiz 225. doi: 10.1016/j.eururo.2007.10.005. Epub 2007 Oct 12.

Abstract

The current practice of withdrawing antiplatelet therapy before major surgery has been challenged by the introduction of coronary drug-eluting stents (DESs) since evidence is accumulating that a DES requires dual antiplatelet therapy for at least a year. The authors present a case demonstrating difficulty in decision-making when it comes to appropriate perioperative antiplatelet therapy. The patient experienced a coronary stent thrombosis possibly due to discontinuation of clopidogrel prior to urologic surgery.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Clopidogrel
  • Coronary Stenosis / complications
  • Coronary Stenosis / therapy*
  • Drug-Eluting Stents / adverse effects*
  • Fatal Outcome
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Lymph Node Excision*
  • Male
  • Paclitaxel / administration & dosage
  • Platelet Aggregation Inhibitors / administration & dosage*
  • Prostatic Neoplasms / complications
  • Prostatic Neoplasms / pathology*
  • Thrombosis / etiology*
  • Ticlopidine / administration & dosage
  • Ticlopidine / analogs & derivatives*
  • Withholding Treatment

Substances

  • Immunosuppressive Agents
  • Platelet Aggregation Inhibitors
  • Clopidogrel
  • Ticlopidine
  • Paclitaxel