Metastatic hepatocellular carcinoma in the urinary bladder with radiation-induced hemorrhagic cystitis

J Formos Med Assoc. 2007 Oct;106(10):861-3. doi: 10.1016/S0929-6646(08)60052-2.

Abstract

Metastatic hepatocellular carcinoma (HCC) to the urinary bladder is very rare. We present the case of a 58-year-old female patient who was diagnosed to have both HCC and cervical cancer. She developed hemorrhagic cystitis 2 years after radiation therapy for cervical cancer. During endoscopic electrocauterization for hemorrhagic cystitis, three small reddish tumors measuring less than 1 cm in diameter and with a raspberry-like appearance were found. Transurethral bladder tumor resection was performed. Pathology confirmed metastatic HCC to the bladder. Due to the similar appearance, these tumors are liable to be misinterpreted as engorged vessels secondary to irradiation if biopsies are not taken. Differential diagnosis by pathology is mandatory for such patients.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Hepatocellular / pathology*
  • Cystitis / etiology*
  • Female
  • Hemorrhage / etiology*
  • Humans
  • Liver Neoplasms / pathology*
  • Middle Aged
  • Radiotherapy / adverse effects
  • Urinary Bladder Neoplasms / diagnosis
  • Urinary Bladder Neoplasms / secondary*
  • Uterine Cervical Neoplasms / radiotherapy