[Use of diafiltration in the lavage of cultures of Leptospira interrogans canicola canicola for the production of vaccine vax-SPIRAL]

Kenia Fernández Enrique; José Daniel Benitez Zamora; Raúl Boué Gutiérrez; Florinda Hernández Torres; Janet Lazo Airado; Damián Rojo Hernández

[Use of diafiltration in the lavage of cultures of Leptospira interrogans canicola canicola for the production of vaccine vax-SPIRAL]

Rev Cubana Med Trop. 2005 Jan-Apr;57(1):69-70.

[Article in Spanish]

Authors

Kenia Fernández Enrique¹, José Daniel Benitez Zamora, Raúl Boué Gutiérrez, Florinda Hernández Torres, Janet Lazo Airado, Damián Rojo Hernández

Affiliation

¹ Instituto Finlay, Ciudad de La Habana, Cuba.

PMID: 17966488

Abstract

It was proposed to substitute the present technology of the lavage operation for a tangential microfiltration system at the lavage stages of the culture of Leptospira interrogans canicola canicola. It was proved that this system may be applied, since no cellular affectation was observed and high pollutant elimination levels were obtained.

Publication types

English Abstract

MeSH terms

Bacterial Vaccines* / economics
Bacterial Vaccines* / immunology
Bacterial Vaccines* / standards
Bacteriological Techniques
Cuba
Filtration
Humans
Leptospira interrogans serovar canicola / growth & development*
Leptospira interrogans serovar canicola / immunology*
Leptospirosis / prevention & control*
Time Factors

Substances

Bacterial Vaccines