Abstract
We present the case of a 71-year old man with acute eosinophilic pneumonia. By ruling out other common etiologies and by a positive lymphocyte transformation test the non-steroidal anti-inflammatory drug mefenamic acid was identified as the possible causative agent or this potentially life threatening lung disease. The clinical presentation, diagnosis, and treatment of acute eosinophilic pneumonia as a pulmonary manifestation of a drug-induced allergic reaction are discussed.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Aged
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Anti-Inflammatory Agents, Non-Steroidal / adverse effects*
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Bronchoalveolar Lavage Fluid / immunology
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Diagnosis, Differential
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Drug Hypersensitivity / diagnosis*
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Drug Hypersensitivity / pathology
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Eosinophilia / etiology*
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Eosinophils / pathology
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Fever of Unknown Origin / etiology*
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Humans
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Male
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Mefenamic Acid / adverse effects*
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Mefenamic Acid / therapeutic use
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Osteoarthritis, Hip / drug therapy*
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Pulmonary Eosinophilia / chemically induced*
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Pulmonary Eosinophilia / diagnosis
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Pulmonary Eosinophilia / pathology
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Mefenamic Acid