Patterns of practice of palliative radiotherapy in Africa, Part 1: Bone and brain metastases

Int J Radiat Oncol Biol Phys. 2008 Mar 15;70(4):1195-201. doi: 10.1016/j.ijrobp.2007.07.2381. Epub 2007 Oct 29.

Abstract

Purpose: To provide data on the pattern of practice of palliative radiotherapy (RT) on the African continent.

Methods and materials: A questionnaire was distributed to participants in a regional training course of the International Atomic Energy Agency in palliative cancer care and sent by e-mail to other institutions in Africa. Requested information included both infrastructure and human resources available and the pattern of RT practice for metastatic and locally advanced cancers.

Results: Of 35 centers contacted, 24 (68%) completed the questionnaire. Although RT is used by most centers for most metastatic cancers, liver and lung metastases are treated with chemotherapy. Of 23 centers, 14 (61%) had a single RT regimen as an institutional policy for treating painful bone metastases, but only 5 centers (23%) of 23 used 8 Gy in 1 fraction. Brain metastases were being treated by RT to the whole brain to 30 Gy in 10 fractions, either exclusively (n=13, 56%) or in addition to the use of 20 Gy in 5 fractions (n=3, 14%).

Conclusion: Radiotherapy is a major component of treatment of cancer patients in African countries. There is consensus among few centers for treatment schedules for almost all sites regarding time and dose-fractionation characteristics of RT regimens used and/or indications for the use of RT in this setting.

Publication types

  • Multicenter Study

MeSH terms

  • Africa
  • Bone Diseases / radiotherapy
  • Bone Neoplasms / radiotherapy*
  • Bone Neoplasms / secondary
  • Brain Neoplasms / radiotherapy*
  • Brain Neoplasms / secondary
  • Health Care Surveys
  • Humans
  • Pain / radiotherapy
  • Palliative Care / statistics & numerical data*
  • Radiation Oncology / statistics & numerical data*
  • Radiotherapy / instrumentation
  • Radiotherapy Dosage
  • Workforce