Approach to term neonates born after maternal intrapartum fever and unknown maternal group B Streptococcus status: value of serum C-reactive protein and 16S rRNA gene PCR amplification

Pediatr Infect Dis J. 2007 Nov;26(11):1064-6. doi: 10.1097/INF.0b013e31812f5701.

Abstract

Thirty-six term neonates born after maternal intrapartum fever, with premature rupture of membranes <18 hours and unknown maternal group B Streptococcus status had blood samples for complete blood count, C-reactive protein, culture, and 16S rRNA gene polymerase chain reaction amplification. Only 2 neonates were symptomatic and none had leukopenia, C-reactive protein >1.0 mg/dL, bacteremia, or positive polymerase chain reaction.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Bacteremia* / diagnosis
  • Bacteremia* / drug therapy
  • Bacteremia* / microbiology
  • Bacteremia* / physiopathology
  • C-Reactive Protein / analysis*
  • Chemoprevention
  • Female
  • Fetal Membranes, Premature Rupture* / drug therapy
  • Fetal Membranes, Premature Rupture* / microbiology
  • Fetal Membranes, Premature Rupture* / physiopathology
  • Fever* / drug therapy
  • Fever* / etiology
  • Humans
  • Infant, Newborn
  • Male
  • Polymerase Chain Reaction / methods*
  • Pregnancy
  • RNA, Ribosomal, 16S / genetics*
  • Streptococcal Infections / diagnosis
  • Streptococcal Infections / drug therapy
  • Streptococcal Infections / microbiology
  • Streptococcal Infections / physiopathology
  • Streptococcus agalactiae* / classification
  • Streptococcus agalactiae* / genetics
  • Streptococcus agalactiae* / isolation & purification

Substances

  • Anti-Bacterial Agents
  • RNA, Ribosomal, 16S
  • C-Reactive Protein