Abstract
Monoamine Oxidase Reporters 1 and 2 (MR1 and MR2) are substrate-tethered activity probes that utilize a tandem amine oxidation/beta-elimination mechanism to detect MAO chemistry in vitro and in living cells directly and specifically without the need for additional enzymes or other activating reagents.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Enzyme Activation
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Fluorescent Dyes / chemical synthesis
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Fluorescent Dyes / chemistry*
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Molecular Structure
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Monoamine Oxidase / chemistry*
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PC12 Cells
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Rats
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Time Factors
Substances
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Fluorescent Dyes
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Monoamine Oxidase