Osteoporosis in patients affected with thalassemia. Our experience

Chir Organi Mov. 1991 Oct-Dec;76(4):369-74.
[Article in English, Italian]

Abstract

The authors examine 72 patients affected with homozygous B-thalassemia; The study was conducted by clinical-hematological and radiologic examination. The Singh method is used to compare clinical data with the degree of osteoporosis. The results indicate that there is a high frequency of osteoporotic abnormalities in thalassemia. The authors postulate that osteoporotic lesions are principally caused by hyperplasia of the marrow, the overactive bone marrow widening the medullary space and the increased intramedullary pressure causing osteoporosis.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Blood Transfusion
  • Bone Density
  • Bone Diseases, Metabolic / diagnosis
  • Bone Diseases, Metabolic / diagnostic imaging
  • Bone Diseases, Metabolic / etiology
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Infant
  • Male
  • Osteoporosis / diagnosis
  • Osteoporosis / diagnostic imaging
  • Osteoporosis / etiology*
  • Radiography
  • Thalassemia / complications*
  • Thalassemia / therapy