Abstract
The mechanisms by which arrhythmias are generated in the heart remains a field of intensive research. Recent advances in computational biology and electrophysiology have enabled researchers to use an alternative tool in the study of arrhythmia mechanisms, the multi-scale modeling and simulation of cardiac arrhythmogenesis at the organ level. This article reviews the recent advances and achievements using this approach.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Arrhythmias, Cardiac / etiology*
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Arrhythmias, Cardiac / pathology
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Arrhythmias, Cardiac / physiopathology
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Cardiac Electrophysiology
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Computational Biology / methods
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Heart / anatomy & histology
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Humans
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Imaging, Three-Dimensional / methods
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Models, Cardiovascular*
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Rabbits