Volume mesh generation and finite element analysis of trabecular bone magnetic resonance images

Annu Int Conf IEEE Eng Med Biol Soc. 2007:2007:1603-6. doi: 10.1109/IEMBS.2007.4352612.

Abstract

In order to help the assessment of trabecular bone diseases and complement Dual X-Ray Absorptiometry (DXA) in diagnosis process, it is needed an accurate mechanical characterization of trabecular bone structure to estimate the risk of fracture and evaluate micro-architecture deterioration. As Finite Element modeling has become a well-established method for analysis of complex structures, an algorithm has been developed to build a Finite Element mesh from three-dimensional reconstruction information in voxels. Generated mesh is loaded in a Finite Element analysis software in order to simulate micro-architecture mechanical behavior under compression conditions. Most part of related researches have been based on ex vivo micro-Computed Tomography (microCT) scans. This study uses three-dimensional trabecular bone reconstructions from high resolution Magnetic Resonance images acquired in vivo.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Animals
  • Bone and Bones / cytology*
  • Bone and Bones / physiology*
  • Computer Simulation
  • Elasticity
  • Finite Element Analysis
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Magnetic Resonance Imaging / methods*
  • Models, Biological*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Stress, Mechanical