Triterpene, antioxidant, and antimicrobial compounds from Melissa officinalis

J Nat Prod. 2007 Dec;70(12):1889-94. doi: 10.1021/np070351s. Epub 2007 Nov 16.

Abstract

Six new triterpenes (1- 6) and four known compounds have been isolated from dried stems and leaves of Melissa officinalis. The known compounds were identified as quadranoside III, salvianic acid A, rosmarinic acid, and luteolin. The structures of compounds 1- 6 were established by analysis of spectroscopic data. Free radical scavenging and antimicrobial activities of the extracts and of rosmarinic acid, the major component, were evaluated.

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / isolation & purification*
  • Anti-Infective Agents / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification*
  • Antioxidants / pharmacology*
  • Biphenyl Compounds
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / isolation & purification
  • Free Radical Scavengers / pharmacology*
  • Italy
  • Melissa / chemistry*
  • Molecular Structure
  • Picrates / pharmacology
  • Plant Leaves / chemistry
  • Plant Stems / chemistry
  • Plants, Medicinal / chemistry*
  • Triterpenes / chemistry
  • Triterpenes / isolation & purification*
  • Triterpenes / pharmacology*

Substances

  • Anti-Infective Agents
  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Picrates
  • Triterpenes
  • 1,1-diphenyl-2-picrylhydrazyl