Abstract
A 48-year-old man presented with acute chest pain and a greatly increased platelet count. Emergency coronary angiographic revealed thrombotic occlusion of the right coronary artery. Coronary angioplasty and stenting were successfully combined with intracoronary abciximab administration. Due to inadequate postinterventional platelet inhibition an intensified dual antiplatelet therapy with acetylsalicylic acid (ASS) and clopidogrel was applied to prevent stent thrombosis. Due to the thrombo-embolic complication and a platelet count over 1 million/microl a cytoreductive treatment with hydroxyurea was initiated.
MeSH terms
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Abciximab
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Angioplasty, Balloon, Coronary
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Antibodies, Monoclonal / therapeutic use
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Biopsy, Needle
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Bone Marrow / pathology
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Combined Modality Therapy
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Coronary Angiography
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Coronary Thrombosis / diagnosis*
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Coronary Thrombosis / therapy
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Electrocardiography*
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Humans
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Immunoglobulin Fab Fragments / therapeutic use
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Male
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Middle Aged
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Myeloproliferative Disorders / diagnosis
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Myeloproliferative Disorders / therapy
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Myocardial Infarction / diagnosis*
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Myocardial Infarction / therapy
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Platelet Aggregation Inhibitors / therapeutic use
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Stents
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Thrombocytosis / diagnosis*
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Thrombocytosis / therapy
Substances
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Antibodies, Monoclonal
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Immunoglobulin Fab Fragments
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Platelet Aggregation Inhibitors
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Abciximab