The regulatory T cell transcriptosome: E pluribus unum

Talal Chatila

doi:10.1016/j.immuni.2007.11.004

The regulatory T cell transcriptosome: E pluribus unum

Immunity. 2007 Nov;27(5):693-5. doi: 10.1016/j.immuni.2007.11.004.

Author

Talal Chatila¹

Affiliation

¹ Division of Immunology, Allergy and Rheumatology, Department of Pediatrics, The David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, CA 90095, USA. [email protected]

PMID: 18031692
DOI: 10.1016/j.immuni.2007.11.004

Abstract

The regulatory T (Treg) cell transcriptional program is formed of distinct genetic networks that respond to different activators. In this issue of Immunity, Hill et al. (2007) provide insights into the interactions among the different networks and the overall role of Foxp3 in shaping the Treg cell transcriptosome.

Publication types

Comment
Review

MeSH terms

Animals
Forkhead Transcription Factors / genetics
Forkhead Transcription Factors / immunology*
Gene Expression Profiling*
Humans
Lymphocyte Activation / genetics
Lymphocyte Activation / immunology
Signal Transduction / genetics
Signal Transduction / immunology*
T-Lymphocytes, Regulatory / immunology*

Substances

FOXP3 protein, human
Forkhead Transcription Factors