Ptilomycalin D, a polycyclic guanidine alkaloid from the marine sponge Monanchora dianchora

J Nat Prod. 2007 Dec;70(12):2033-5. doi: 10.1021/np070340z. Epub 2007 Nov 27.

Abstract

A new polycyclic guanidine alkaloid, ptilomycalin D, and the known crambescidic acid were isolated from the marine sponge Monanchora dianchora collected in Nosy-Be, northwest of Madagascar, in the Indian Ocean. The structures were elucidated using 1- and 2-D NMR and MS data, and their biogenetic implications are discussed.

MeSH terms

  • Alkaloids / chemistry*
  • Alkaloids / isolation & purification*
  • Animals
  • Guanidines / chemistry*
  • Guanidines / isolation & purification*
  • Indian Ocean
  • Madagascar
  • Marine Biology
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Porifera / chemistry*

Substances

  • Alkaloids
  • Guanidines
  • ptilomycalin A
  • ptilomycalin D