[Studies on chemical constituents from root of Cynanchum atratum]

Zhongguo Zhong Yao Za Zhi. 2007 Sep;32(18):1895-8.
[Article in Chinese]

Abstract

Objective: To study the chemical constituents from the roots and rhizome of Cynanchum atratum.

Method: The chemical constituents were isolated and repeatedly purified by silica gel chromatography and the structures were elucidated by the NMR spectra and physicochemical properties.

Result: Twelve compounds were obtained and nine of them were identified as 2, 4-dihyroxyacetophe none (1), 2, 6-dihyroxyacetophenone (2), 4-hydroxybenzenemethanol (3), benzoic acid (4), beta-amyrin acetate (5), palmitic acid (6), beta-sitosterol (7), beta-daucosterol (8), glaucogenin C-3-O-alpha-D-oleandropyranosyl-(1 --> 4)-beta-D-digitoxopyranosyl-(1 -->4)-alpha-D-oleandropyranoside (9).

Conclusion: Seven compounds were obtained from C. atratum for the first time.

MeSH terms

  • Benzoic Acid / chemistry
  • Benzoic Acid / isolation & purification*
  • Chromatography, Gel
  • Cynanchum / chemistry*
  • Oleanolic Acid / analogs & derivatives*
  • Oleanolic Acid / chemistry
  • Oleanolic Acid / isolation & purification
  • Palmitic Acid / chemistry
  • Palmitic Acid / isolation & purification*
  • Plant Roots / chemistry*
  • Plants, Medicinal / chemistry
  • Silica Gel
  • Silicon Dioxide

Substances

  • Palmitic Acid
  • Silica Gel
  • Oleanolic Acid
  • Silicon Dioxide
  • Benzoic Acid
  • beta-amyrin acetate