Diffuse lamellar keratitis after corneal crosslinking in a patient with post-laser in situ keratomileusis corneal ectasia

J Cataract Refract Surg. 2007 Dec;33(12):2135-7. doi: 10.1016/j.jcrs.2007.06.070.

Abstract

A 27-year-old man presented with corneal ectasia in his left eye 4 years after myopic laser in situ keratomileusis (LASIK) and was treated with riboflavin-ultraviolet-A (crosslinking). During the first post-treatment days, diffuse lamellar keratitis (DLK) (stage III) developed. The microbiology culture was negative. After intensive treatment with topical corticosteroids, the DLK resolved during the following 2 weeks. Crosslinking for post-LASIK corneal ectasia may induce DLK. Early diagnosis and appropriate treatment with intensive topical corticosteroids is essential to successfully manage this post-crosslinking complication.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Collagen / metabolism*
  • Corneal Diseases / drug therapy*
  • Corneal Diseases / etiology
  • Corneal Diseases / metabolism
  • Dexamethasone / therapeutic use
  • Dilatation, Pathologic / drug therapy
  • Dilatation, Pathologic / etiology
  • Dilatation, Pathologic / metabolism
  • Glucocorticoids / therapeutic use
  • Humans
  • Keratitis / drug therapy
  • Keratitis / etiology*
  • Keratomileusis, Laser In Situ / adverse effects*
  • Male
  • Myopia / surgery
  • Photosensitizing Agents / adverse effects*
  • Riboflavin / adverse effects
  • Ultraviolet Rays

Substances

  • Glucocorticoids
  • Photosensitizing Agents
  • Dexamethasone
  • Collagen
  • Riboflavin