[Molecular and therapeutic approaches of the Alzheimer's disease]

Morphologie. 2007 Dec;91(295):221-5. doi: 10.1016/j.morpho.2007.10.012. Epub 2007 Nov 28.
[Article in French]

Abstract

The Alzheimer's disease (AD) is clinically characterized by the progressive appearance of amnesic disorders, which are followed by a clinical syndrome associating aphasia, apraxia and agnosia. In this picture are added behavioural problems, marked for example by decision-making or judgment confusions and disturbances of the orientation. The therapeutic perspectives are based especially on molecular targets that are the peptide Abeta, the protein tau or the facilitating molecular ways of neurodegeneration.

Publication types

  • English Abstract

MeSH terms

  • Aging
  • Agnosia / etiology
  • Alzheimer Disease / genetics*
  • Alzheimer Disease / pathology
  • Alzheimer Disease / physiopathology
  • Alzheimer Disease / psychology
  • Amnesia / etiology
  • Aphasia / etiology
  • Disease Progression
  • Humans
  • tau Proteins

Substances

  • tau Proteins