Development of non-toxigenic vaccine strains of Bordetella pertussis by gene replacement

Adv Exp Med Biol. 1991:303:221-5. doi: 10.1007/978-1-4684-6000-1_24.
No abstract available

MeSH terms

  • Animals
  • Antibodies, Bacterial / biosynthesis
  • Bordetella pertussis / genetics
  • Bordetella pertussis / immunology*
  • Guinea Pigs
  • Mice
  • Mutation
  • Pertussis Vaccine / isolation & purification*
  • Vaccines, Synthetic / isolation & purification
  • Virulence Factors, Bordetella / genetics
  • Virulence Factors, Bordetella / immunology

Substances

  • Antibodies, Bacterial
  • Pertussis Vaccine
  • Vaccines, Synthetic
  • Virulence Factors, Bordetella