Abstract
The potential inhibitory effects of tenofovir and a placebo were examined using the Becton Dickinson ProbeTec, Gen-Probe Aptima Combo 2, and Roche Amplicor tests to detect Chlamydia trachomatis and Neisseria gonorrhoeae. Concentrations of 5% to 0% of tenofovir and the placebo were added to dilutions of C. trachomatis and N. gonorrhoeae. No appreciable inhibition was observed.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Adenine / analogs & derivatives*
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Adenine / pharmacology
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Anti-Infective Agents / pharmacology
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Chlamydia Infections / diagnosis
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Chlamydia trachomatis / genetics
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Chlamydia trachomatis / isolation & purification*
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Female
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Gonorrhea / diagnosis
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Humans
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Male
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Neisseria gonorrhoeae / genetics
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Neisseria gonorrhoeae / isolation & purification*
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Nucleic Acid Amplification Techniques / methods*
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Organophosphonates / pharmacology*
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Reverse Transcriptase Inhibitors / pharmacology*
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Tenofovir
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Urine / microbiology*
Substances
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Anti-Infective Agents
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Organophosphonates
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Reverse Transcriptase Inhibitors
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Tenofovir
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Adenine