Abstract
Glomerulonephritis and pulmonary hemorrhage are features of Goodpasture's syndrome. Goodpasture's syndrome accompanied with central nervous system (CNS) vasculitis is extremely rare. Herein, we report a rare case of CNS vasculitis associated with Goodpasture's syndrome in a 34-year-old man, who presented with a seizure and sudden onset of right sided weakness. He also had recurrent hemoptysis of one month's duration. Goodpasture's syndrome is histologically diagnosed by intense linear deposits of IgG along the glomerular basement membrane in both renal and lung tissues.
MeSH terms
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Adult
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Anti-Glomerular Basement Membrane Disease / complications
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Anti-Glomerular Basement Membrane Disease / diagnosis*
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Anti-Glomerular Basement Membrane Disease / therapy
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Anti-Inflammatory Agents / administration & dosage
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Brain / pathology*
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Contrast Media / administration & dosage
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Diagnosis, Differential
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Fluorescent Antibody Technique
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Hemoptysis / etiology
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Humans
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Image Enhancement / methods
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Immunoglobulin G / immunology
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Kidney / diagnostic imaging
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Lung / diagnostic imaging*
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Lung / pathology
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Magnetic Resonance Imaging
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Male
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Methylprednisolone / administration & dosage
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Muscle Weakness / etiology
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Plasmapheresis
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Rare Diseases
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Seizures / etiology
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Tomography, X-Ray Computed
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Ultrasonography
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Vasculitis, Central Nervous System / diagnosis*
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Vasculitis, Central Nervous System / etiology
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Vasculitis, Central Nervous System / therapy
Substances
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Anti-Inflammatory Agents
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Contrast Media
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Immunoglobulin G
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Methylprednisolone