Abstract
In this article, we review the literature on posttraumatic stress disorder (PTSD) and PTSD-like symptoms that can occur along with mild traumatic brain injury (TBI) and concussion, with specific reference to concussive injuries in the military. We address four major areas: (1) clinical aspects of TBI and PTSD, including diagnostic criteria, incidence, predictive factors, and course; (2) biological overlap between PTSD and TBI; (3) comorbidity between PTSD and other mental disorders that can occur after mild TBI; and (4) current treatments for PTSD, with specific considerations related to treatment for patients with mild TBI or concussive injuries.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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Adaptation, Physiological
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Adaptation, Psychological
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Animals
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Antidepressive Agents / therapeutic use
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Brain Injuries / epidemiology*
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Brain Injuries / physiopathology
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Brain Injuries / psychology
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Brain Injuries / rehabilitation*
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Comorbidity
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Humans
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Mental Disorders / epidemiology
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Military Personnel*
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Psychotherapy / methods
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Stress Disorders, Post-Traumatic / epidemiology*
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Stress Disorders, Post-Traumatic / genetics
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Stress Disorders, Post-Traumatic / physiopathology
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Stress Disorders, Post-Traumatic / rehabilitation*
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Synaptic Transmission
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Warfare