Posttraumatic stress disorder and posttraumatic stress disorder-like symptoms and mild traumatic brain injury

J Rehabil Res Dev. 2007;44(7):895-920. doi: 10.1682/jrrd.2006.12.0166.

Abstract

In this article, we review the literature on posttraumatic stress disorder (PTSD) and PTSD-like symptoms that can occur along with mild traumatic brain injury (TBI) and concussion, with specific reference to concussive injuries in the military. We address four major areas: (1) clinical aspects of TBI and PTSD, including diagnostic criteria, incidence, predictive factors, and course; (2) biological overlap between PTSD and TBI; (3) comorbidity between PTSD and other mental disorders that can occur after mild TBI; and (4) current treatments for PTSD, with specific considerations related to treatment for patients with mild TBI or concussive injuries.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Adaptation, Physiological
  • Adaptation, Psychological
  • Animals
  • Antidepressive Agents / therapeutic use
  • Brain Injuries / epidemiology*
  • Brain Injuries / physiopathology
  • Brain Injuries / psychology
  • Brain Injuries / rehabilitation*
  • Comorbidity
  • Humans
  • Mental Disorders / epidemiology
  • Military Personnel*
  • Psychotherapy / methods
  • Stress Disorders, Post-Traumatic / epidemiology*
  • Stress Disorders, Post-Traumatic / genetics
  • Stress Disorders, Post-Traumatic / physiopathology
  • Stress Disorders, Post-Traumatic / rehabilitation*
  • Synaptic Transmission
  • Warfare

Substances

  • Antidepressive Agents