Complete pathological response following down-staging chemoradiation in locally advanced pancreatic cancer: challenging the boundaries

World J Gastroenterol. 2007 Dec 21;13(47):6433-5. doi: 10.3748/wjg.v13.i47.6433.

Abstract

Pancreatic cancer is an aggressive malignancy, relatively resistant to chemotherapy and radiotherapy, which usually presents late. Disease specific mortality approaches unity despite advances in adjuvant therapy. We present the first reported case of complete pathological response following neoadjuvant therapy in a locally advanced pancreatic adenocarcinoma.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / drug therapy*
  • Adenocarcinoma / pathology
  • Adenocarcinoma / radiotherapy*
  • Adenocarcinoma / surgery
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Chemotherapy, Adjuvant
  • Humans
  • Male
  • Neoadjuvant Therapy
  • Neoplasm Invasiveness
  • Pancreatic Neoplasms / drug therapy*
  • Pancreatic Neoplasms / pathology
  • Pancreatic Neoplasms / radiotherapy*
  • Pancreatic Neoplasms / surgery
  • Pancreaticoduodenectomy
  • Radiotherapy, Adjuvant
  • Tomography, X-Ray Computed
  • Treatment Outcome