Abstract
Anticonvulsants have been used for the treatment of impulsive aggression since the 1980s. A 50-year-old man suffered from irritability and agitation after developing a right ipsilateral frontal lobe infarction as a result of Moyamoya disease; these symptoms caused difficulties with his working and interpersonal relationships. The patient had been treated using multiple benzodiazepine agents for 2 years but his symptoms had not improved. However, after treatment with carbamazepine (CBZ; 200 mg) was begun, the patient's irritability and agitation gradually decreased. The efficacy of CBZ treatment in this patient suggests a method for controlling benzodiazepine-resistant impulsive aggression.
MeSH terms
-
Aggression / drug effects*
-
Aggression / psychology
-
Antimanic Agents / therapeutic use*
-
Benzodiazepines / therapeutic use*
-
Carbamazepine / therapeutic use*
-
Cerebral Infarction / complications*
-
Cerebral Infarction / pathology
-
Cerebral Infarction / psychology*
-
Drug Resistance
-
Electroencephalography
-
Frontal Lobe / pathology*
-
Humans
-
Hypnotics and Sedatives / therapeutic use*
-
Impulsive Behavior / drug therapy*
-
Impulsive Behavior / etiology
-
Impulsive Behavior / psychology
-
Irritable Mood / drug effects
-
Male
-
Middle Aged
-
Moyamoya Disease / complications*
-
Moyamoya Disease / pathology*
-
Paresthesia / drug therapy
-
Psychomotor Agitation / drug therapy
-
Psychomotor Agitation / etiology
Substances
-
Antimanic Agents
-
Hypnotics and Sedatives
-
Benzodiazepines
-
Carbamazepine