Abstract
We evaluated the frequency of primary central nervous system lymphoma and leptomeningeal involvement in systemic non-Hodgkin's lymphoma (NHL) in HIV-infected patients. Those receiving highly active antiretroviral therapy (HAART) showed a decrease in leptomeningeal involvement in systemic NHL (0/30 vs. 12/87; p=0.023). Therefore HAART could prevent CNS involvement in systemic NHL.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Acquired Immunodeficiency Syndrome / diagnosis*
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Acquired Immunodeficiency Syndrome / drug therapy*
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Adult
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Antiretroviral Therapy, Highly Active*
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Disease Progression
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Female
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Humans
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Lymphoma, AIDS-Related / diagnosis*
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Lymphoma, AIDS-Related / prevention & control*
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Male
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Meninges / pathology*
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Prognosis
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Retrospective Studies
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Time Factors