Bone apposition around two different sandblasted and acid-etched titanium implant surfaces: a histomorphometric study in canine mandibles

Clin Oral Implants Res. 2008 Mar;19(3):233-41. doi: 10.1111/j.1600-0501.2007.01473.x. Epub 2008 Jan 3.

Abstract

Purpose: The aim of this study was to evaluate bone apposition to a modified sandblasted and acid-etched (SLA) implant surface (modSLA) in the canine mandible as compared with the standard SLA surface.

Material and methods: In this experimental study, all mandibular premolars and first molars were extracted bilaterally in five foxhounds. After a healing period of 6 months, each side of the mandible received six randomly assigned dental implants alternating between the standard SLA and modSLA surface. The dogs were sacrificed at 2 weeks (n=2) or 4 weeks (n=3) after implant placement. Histologic and histomorphometric analyses were then performed for each implant.

Results: The microscopic healing patterns at weeks 2 and 4 for the two implant types with the standard SLA and modSLA surfaces showed similar qualitative findings. New bone tissue had already established direct contact with implant surfaces after 2 weeks of healing. The mean percentage of newly formed bone in contact with the implant (BIC) was significantly greater for modSLA (28.2+/-7.9%) than for SLA (22.2+/-7.3%) (P<0.05). This difference was no longer evident after 4 weeks. An increase in BIC for both implant surface types occurred from weeks 2 to 4. This increase was statistically significant when compared with SLA at 2 weeks (P<0.05), but not when compared with modSLA at 2 weeks.

Conclusion: The data from the present study demonstrate significantly more bone apposition for the modSLA surface than the standard SLA surface after 2 weeks of healing. This increased bone apposition may allow a further reduction of the healing period following implant placement for patients undergoing early loading procedures.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bone Matrix / blood supply*
  • Dental Etching / methods
  • Dental Implantation, Endosseous*
  • Dental Implants*
  • Dental Prosthesis Design*
  • Dogs
  • Implants, Experimental
  • Male
  • Mandible / surgery
  • Nitrogen / pharmacology
  • Osseointegration*
  • Random Allocation
  • Sodium Chloride
  • Surface Properties
  • Titanium / chemistry
  • Wettability / drug effects

Substances

  • Dental Implants
  • Sodium Chloride
  • Titanium
  • Nitrogen