A non-endocrine cause of testicular enlargement mimicking precocious puberty: testicular microlithiasis

J Pediatr Endocrinol Metab. 2007 Nov;20(11):1237-40. doi: 10.1515/jpem.2007.20.11.1237.

Abstract

Untimely bilateral testicular enlargement greater than 3 ml is suggestive of precocious puberty, in which an underlying organic disease is more common in boys than in girls. We describe a 7 1/2 year-old boy presenting with testicular enlargement due to testicular microlithiasis. Following hormonal tests, diagnosis was based on ultrasonographic findings. Three years follow-up of the patient revealed normal pubertal progress and no malignant evolution. Testicular microlithiasis is a rare cause of testicular enlargement and pediatricians should take this disease into account in the differential diagnosis of suspected precocious puberty.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Diagnosis, Differential
  • Follicle Stimulating Hormone / blood
  • Gonadotropin-Releasing Hormone / blood
  • Humans
  • Hypertrophy
  • Lithiasis / diagnosis*
  • Lithiasis / diagnostic imaging
  • Luteinizing Hormone / blood
  • Male
  • Puberty, Precocious / diagnosis*
  • Testicular Diseases / blood
  • Testicular Diseases / diagnosis*
  • Testicular Diseases / diagnostic imaging
  • Testis / diagnostic imaging
  • Testis / pathology*
  • Testosterone / blood
  • Ultrasonography

Substances

  • Gonadotropin-Releasing Hormone
  • Testosterone
  • Luteinizing Hormone
  • Follicle Stimulating Hormone