[Primary hypothyroidism and glomerular involvement]

Ann Endocrinol (Paris). 1991;52(4):289-92.
[Article in French]

Abstract

Association between auto-immune dysthyroidism and glomerulonephritis is quite rare. The authors report 3 cases with proteinuria varying from 2.72 to 6.06 g/day and hypothyroidism. Nephrotic syndrome was found in 2 cases and thyroid auto-antibodies (microsomal and thyroglobulin) and circulating immun complexes (C.I.C.) in 1 case, complement fractions C3 and C4 were normal in all cases. Renal biopsy showed membranous glomerulonephritis in 2 cases and minimal lesions in the third case. Proteinuria disappeared with glucocorticoids and thyroxine in 1 case, with thyroxine alone in an other case and persisted in the third case with normal thyroid function.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Female
  • Glomerulonephritis / complications*
  • Glomerulonephritis / diagnosis
  • Humans
  • Hypothyroidism / complications*
  • Male
  • Middle Aged