Long-lived two-photon excited luminescence of water-soluble europium complex: applications in biological imaging using two-photon scanning microscopy

Alexandre Picot; Anthony D'Aléo; Patrice L Baldeck; Alexei Grichine; Alain Duperray; Chantal Andraud; Olivier Maury

doi:10.1021/ja076837c

Long-lived two-photon excited luminescence of water-soluble europium complex: applications in biological imaging using two-photon scanning microscopy

J Am Chem Soc. 2008 Feb 6;130(5):1532-3. doi: 10.1021/ja076837c. Epub 2008 Jan 15.

Authors

Alexandre Picot¹, Anthony D'Aléo, Patrice L Baldeck, Alexei Grichine, Alain Duperray, Chantal Andraud, Olivier Maury

Affiliation

¹ Université de Lyon, Laboratoire de Chimie, CNRS-ENS Lyon, 46 allée d'Italie 69364 Lyon, France.

Abstract

A new europium complex presenting good solubility and stability in water, intense emission in the red (616 nm), long luminescence lifetime and significant two-photon absorption cross-section in the biological window has been designed and successfully used for two-photon scanning microscopy bio-imaging experiments on fixed cancer cells.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Europium / chemistry*
Luminescent Measurements
Microscopy, Fluorescence, Multiphoton
Molecular Structure
Solubility
Water / chemistry*

Substances

Water
Europium