Abstract
The presence of the genes engBF (endo-alpha-N-acetylgalactosaminidase) and afcA (1,2-alpha-L-fucosidase) was detected in several intestinal Bifidobacterium isolates. Two strains of Bifidobacterium bifidum contained both genes, and they were able to degrade high-molecular weight porcine mucin in vitro. The expression of both genes was highly induced in the presence of mucin.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Bacterial Proteins / genetics
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Bacterial Proteins / metabolism
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Bifidobacterium / classification
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Bifidobacterium / genetics
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Bifidobacterium / metabolism*
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Humans
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Intestines / microbiology*
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Molecular Sequence Data
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Mucins / metabolism*
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Phylogeny
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Swine
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alpha-L-Fucosidase / genetics
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alpha-L-Fucosidase / metabolism
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alpha-N-Acetylgalactosaminidase / genetics
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alpha-N-Acetylgalactosaminidase / metabolism
Substances
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Bacterial Proteins
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Mucins
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alpha-N-Acetylgalactosaminidase
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alpha-L-Fucosidase
Associated data
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GENBANK/EU260397
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GENBANK/EU260398
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GENBANK/EU260399
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GENBANK/EU260400
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GENBANK/EU260401
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GENBANK/EU260402
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GENBANK/EU260403
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GENBANK/EU260404
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GENBANK/EU260405
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GENBANK/EU260406
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GENBANK/EU260407
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GENBANK/EU260408
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GENBANK/EU260409
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GENBANK/EU260410
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GENBANK/EU260411
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GENBANK/EU260412
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GENBANK/EU260413
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GENBANK/EU260414