Discrimination of prostate cancer cells and non-malignant cells using secondary ion mass spectrometry

Analyst. 2008 Feb;133(2):175-9. doi: 10.1039/b712853c. Epub 2007 Nov 30.

Abstract

This communication utilises Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) combined with multivariate analysis to obtain spectra from the surfaces of three closely related cell lines allowing their discrimination based upon mass spectral ions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Discriminant Analysis
  • Humans
  • Male
  • Principal Component Analysis / methods
  • Prostatic Neoplasms / diagnosis*
  • Spectrometry, Mass, Secondary Ion / methods*