Pseudoprogression of lung cancer after concomitant chemoradiotherapy

Eiki Ichihara; Katsuyuki Kiura; Nagio Takigawa; Masako Omori; Motoi Aoe; Mitsune Tanimoto; Hiroshi Date

doi:10.1093/jjco/hym166

Pseudoprogression of lung cancer after concomitant chemoradiotherapy

Jpn J Clin Oncol. 2008 Feb;38(2):140-2. doi: 10.1093/jjco/hym166. Epub 2008 Feb 1.

Authors

Eiki Ichihara¹, Katsuyuki Kiura, Nagio Takigawa, Masako Omori, Motoi Aoe, Mitsune Tanimoto, Hiroshi Date

Affiliation

¹ Department of Hematology, Oncology and Respiratory Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata, Okayama, Okayama 700-8558, Japan.

PMID: 18245515
DOI: 10.1093/jjco/hym166

Abstract

We observed re-enlargement of a squamous cell carcinoma without recurrence. The tumour regressed markedly after concomitant chemoradiotherapy, but within 1 month, we supposed that the tumour had enlarged again and resection was performed. The resected tissue showed evidence of haemorrhage and several lymphocytes and macrophages, but no malignant cells were detected. We herein report a rare case of lung cancer showing a pathological complete response despite re-enlargement of tumour lesion.

Publication types

Case Reports

MeSH terms

Carcinoma, Squamous Cell* / drug therapy
Carcinoma, Squamous Cell* / pathology
Carcinoma, Squamous Cell* / radiotherapy
Carcinoma, Squamous Cell* / surgery
Chemotherapy, Adjuvant
Disease Progression
Hemorrhage
Humans
Lung Neoplasms* / drug therapy
Lung Neoplasms* / pathology
Lung Neoplasms* / radiotherapy
Lung Neoplasms* / surgery
Male
Middle Aged
Neoplasm Recurrence, Local* / pathology
Neoplasm Recurrence, Local* / surgery
Radiotherapy, Adjuvant
Tomography, X-Ray Computed