Advantages of F(ab')2 fragments of anti-CD3 monoclonal antibody as compared to whole antibody as immunosuppressive agents in mice

Transplant Proc. 1991 Feb;23(1 Pt 1):270-1.

Authors

R Hirsch¹, J A Bluestone, C V Bare, R E Gress

Affiliation

¹ Experimental Immunology Branch, NCI, National Institutes of Health, Bethesda, MD 20892.

PMID: 1824981

No abstract available

Publication types

Comparative Study

MeSH terms

Animals
Antibodies, Monoclonal / therapeutic use*
Antigens, Differentiation, T-Lymphocyte / immunology*
CD3 Complex
Graft Rejection
Graft Survival*
Immunoglobulin Fab Fragments / therapeutic use*
Immunosuppression Therapy*
Mice
Receptors, Antigen, T-Cell / immunology*
Skin Transplantation / immunology*
T-Lymphocytes, Cytotoxic / immunology
Transplantation, Homologous

Substances

Antibodies, Monoclonal
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
Immunoglobulin Fab Fragments
Receptors, Antigen, T-Cell