Abstract
Adamantane-resistant influenza A is an emerging problem, but infections caused by resistant and susceptible viruses have not been compared. We identified adamantane resistance in 47% of 152 influenza A virus (H3N2) isolates collected during 2005. Resistant and susceptible viruses caused similar symptoms and illness duration. The prevalence of resistance was highest in children.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adamantane / therapeutic use*
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Adolescent
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Adult
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Aged
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Antiviral Agents / therapeutic use*
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Child
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Child, Preschool
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Cohort Studies
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Disease Outbreaks*
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Drug Resistance, Viral / genetics*
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Female
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Humans
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Infant
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Influenza A Virus, H3N2 Subtype* / drug effects
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Influenza A Virus, H3N2 Subtype* / genetics
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Influenza A Virus, H3N2 Subtype* / isolation & purification
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Influenza B virus / drug effects
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Influenza, Human / drug therapy*
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Influenza, Human / epidemiology
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Influenza, Human / genetics
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Male
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Middle Aged
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Wisconsin / epidemiology
Substances
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Antiviral Agents
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Adamantane