Necrotizing enterocolitis

Pinchi S Srinivasan; Michael D Brandler; Antoni D'Souza

doi:10.1016/j.clp.2007.11.009

Necrotizing enterocolitis

Clin Perinatol. 2008 Mar;35(1):251-72, x. doi: 10.1016/j.clp.2007.11.009.

Authors

Pinchi S Srinivasan¹, Michael D Brandler, Antoni D'Souza

Affiliation

¹ Division of Neonatology, Department of Pediatrics, New York Hospital Queens, Affiliate Weill Medical College of Cornell University, 56-45, Main Street, Flushing, NY 11355, USA. [email protected]

PMID: 18280885
DOI: 10.1016/j.clp.2007.11.009

Abstract

In necrotizing enterocolitis (NEC) the small (most often distal) and/or large bowel becomes injured, develops intramural air, and may progress to frank necrosis with perforation. Even with early, aggressive treatment, the progression of necrosis, which is highly characteristic of NEC, can lead to sepsis and death. This article reviews the current scientific knowledge related to the etiology and pathogenesis of NEC and discusses some possible preventive measures.

Publication types

Review

MeSH terms

Cause of Death
Enterocolitis, Necrotizing / etiology*
Enterocolitis, Necrotizing / prevention & control
Humans
Iatrogenic Disease / prevention & control
Infant, Low Birth Weight
Infant, Newborn
Infant, Premature*
Infant, Premature, Diseases / etiology*
Infant, Premature, Diseases / prevention & control
Risk Factors