Abstract
The evolution of CYP102A1 variants with enhanced activity and altered specificity characteristics.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Bacillus megaterium / enzymology
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Bacterial Proteins / chemistry*
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Bacterial Proteins / genetics
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Bacterial Proteins / isolation & purification
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Benzene Derivatives / chemistry
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Cytochrome P-450 Enzyme System / chemistry*
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Cytochrome P-450 Enzyme System / genetics
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Cytochrome P-450 Enzyme System / isolation & purification
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Directed Molecular Evolution*
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Enzyme Activation
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Mixed Function Oxygenases / chemistry*
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Mixed Function Oxygenases / genetics
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Mixed Function Oxygenases / isolation & purification
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Molecular Structure
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Mutagenesis
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NADPH-Ferrihemoprotein Reductase
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Naphthalenes / chemistry
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Oxidation-Reduction
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Substrate Specificity
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Time Factors
Substances
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Bacterial Proteins
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Benzene Derivatives
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Naphthalenes
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n-propylbenzene
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naphthalene
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Cytochrome P-450 Enzyme System
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Mixed Function Oxygenases
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NADPH-Ferrihemoprotein Reductase
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flavocytochrome P450 BM3 monoxygenases