Progressive macular hypomelanosis in a 16-year old

Pediatr Dermatol. 2008 Jan-Feb;25(1):63-5. doi: 10.1111/j.1525-1470.2007.00585.x.

Abstract

Progressive macular hypomelanosis of the trunk is a disease of unclear etiology that often goes unrecognized in the clinical setting. We present a Caucasian adolescent girl with hypopigmented macules coalescing into patches on her trunk, initially diagnosed as tinea versicolor. Upon further evaluation, the patient was found to have progressive macular hypomelanosis that demonstrated improvement with sunlight exposure and doxycycline. We report this patient to make physicians more aware of this entity and discuss the literature.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Biopsy, Needle
  • Disease Progression
  • Doxycycline / therapeutic use*
  • Female
  • Follow-Up Studies
  • Humans
  • Hypopigmentation / diagnosis*
  • Hypopigmentation / drug therapy*
  • Hypopigmentation / pathology
  • Immunohistochemistry
  • Melanins / metabolism
  • Melanocytes / pathology
  • Severity of Illness Index
  • Skin / metabolism*
  • Skin / pathology
  • Tinea Versicolor / diagnosis*
  • Tinea Versicolor / prevention & control
  • Treatment Outcome

Substances

  • Melanins
  • Doxycycline