Sequencing of subcloned PCR products facilitates earlier detection of BCR-ABL1(T315I) and other mutants compared to direct sequencing of the ABL1 kinase domain

Leukemia. 2008 Apr;22(4):885-8. doi: 10.1038/leu.2008.42. Epub 2008 Feb 28.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • DNA Mutational Analysis / methods*
  • DNA Mutational Analysis / standards
  • Genes, abl / genetics*
  • Humans
  • Middle Aged
  • Point Mutation*
  • Polymerase Chain Reaction
  • Proto-Oncogene Proteins c-abl / genetics*
  • Sequence Analysis, DNA

Substances

  • Proto-Oncogene Proteins c-abl