Children of persons with Alzheimer disease: what does the future hold?

Alzheimer Dis Assoc Disord. 2008 Jan-Mar;22(1):6-20. doi: 10.1097/WAD.0b013e31816653ac.

Abstract

Children of persons with Alzheimer disease (AD), as a group, face an increased risk of developing AD. Many of them, throughout their adult lives, seek input on how to reduce their chances of one day suffering their parent's fate. We examine the state of knowledge with respect to risk and protective factors for AD and recommend a research agenda with special emphasis on AD offspring.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, N.I.H., Intramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adult
  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / genetics*
  • Biomarkers
  • Child
  • Genetic Predisposition to Disease*
  • Humans
  • Pedigree*
  • Risk Factors

Substances

  • Biomarkers